An Rx for Managing Mammography Images and More

By Lisa Vaas  |  Posted 2006-03-27

An Rx for Managing Mammography Images and More

Stage 1 breast cancer tumors are small—less than 2 centimeters in diameter. The mammogram images that can save a womans life are enormous—both in the sense of their critical role in diagnosis and in the fact that they take up a massive amount of storage and hospital floor space.

Thanks to NDMA (National Digital Medical Archive), the fruit of a federally funded project by the University of Pennsylvania, hospitals and clinics such as Murray Hill Radiology are managing to move those images off their own expensive storage systems.

That means getting them off their precious wards and onto NDMAs national network storage system of digital medical images and data, available to patients, physicians, hospitals and researchers through grid computing and a shared archive.

"It saves enormous amounts," said Jill Vincente, practice administrator at Murray Hill Radiology, in New York. "A new [8TB] system [would have been] $150,000 wed have to spend in hardware to replace what we have [now]."

And thats not even counting the impact of having to provide a new location for such a system. A new system would have had to be moved into the network room, which would have had to be piped with new air conditioning and new electricity.

Last but not least, the doctors can finally have their lounge back.

"[The 4TB] system was in the doctors reading room," Vincente said. "Now their legs wont bump against it"—it being a piece of hardware that Vincente described as half the size of a refrigerator and which hummed and radiated heat with fans whirring.

NDMA was created by i3 Archive with the help of IBM. Since the federal project launched in 1999, it has grown to become a nationally coordinated system of 24 hospitals with some 1.5 million digital mammography images that help about 300 doctors diagnose, treat and find a cure for breast cancer.

Open-source software can help cancer researchers. Click here to read more.

NDMA collects mammographies, CT (computerized tomography) scans and MRI (magnetic resonance imaging) images from doctors, hospitals and radiology centers such as Murray Hill Radiology. The service, which links constituents across the country, helps researchers identify and target potential links to breast cancer—and, someday, to other diseases—by providing access to analytical databases and reporting systems.

In addition, i3 Archive launched MyNDMA in November. MyNDMA is a portal that gives women access to and control of their own health records and is also the name of i3 Archives wholly owned subsidiary. One month after the portals launch, nearly 1,200 women had registered profiles to manage their mammography records through the portal.

Derek Danois, president and CEO of i3 Archive, explained that the original federal project was launched because of concern around the large-scale rollout of digital imaging, especially around mammography. People were getting worried, Danois said, about the burdens all this data would impose on private institutions.

That kind of impact can have a direct impact on patient care, Danois said, which is why the government was interested in funding research for alternative storage schemes.

At the core of the archive is IBMs DB2 database. Danois said that i3 used a parallel edition that runs on a grid of DB2 servers, aided by i3s load balancing architecture. IBMs WebSphere middleware is also a component of MyNDMA, and IBMs Rational suite of development tools is used as well.

NDMA is based exclusively on xSeries servers—both at the archive end and at point-of-presence devices employed at hospitals and physicians offices—and uses IBMs FAStT (Fibre Array Storage Technology) storage.

Click here to read a review of IBMs four-way eServer xSeries 460.

Its a "unique architectural design" that uses all off-the-shelf components, said Danois in Berwyn, Pa. The capability to stitch the pieces together freed up the minds behind the service to concentrate on making a difference in how medical images are handled, rather than getting bogged down with creating every piece of the solution from scratch.

"Knowing that IBM had enterprise-class tool sets, I think the intellectual property contribution had to do with those who wanted to take a different approach with computing architecture because of the challenges of large image data sets," Danois said.

Specifically, the challenges of handling such large data sets are quite distinct from the needs of computational data sets that require very fast rates to get pumped through. It has more to do with the need to construct a sophisticated storage structure that could scale to handle, in the United States, about 35 million mammograms a year.

The images range in size from 40MB to 200MB per patient. Early calculations regarding funding on the part of the National Institutes of Health were that if all mammography screenings were converted to digital images, youd have to figure out how to handle 20 petabytes a year—and thats just mammography images, which is a small subset of all medical images.

But it gets worse. Mammography is unique in requiring physicians to pull back a patients prior year or two of images for signs of change. That means a system has to manipulate, distribute and pull back approximately 40 petabytes of images per year.

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Avoiding the

disaster" in disaster recovery">

NDMA now has a fraction of that, with approximately 75TB in each of its two locations, for a total of 1.5 million digital images in the archive. Danois projected that NDMA will grow that to about 10 million images by July or August.

The unanswered question is whether the project can scale. Thus far, Danois said, the architecture is doing "very well" in scaling. i3 plans to bring another 150TB of new storage online in or around June, bringing the total capacity to 250TB.

Because of the way NDMA was designed and its proven scalability and ability to handle medical imaging so well, i3 expanded breast imaging to handle MRIs and CT scans. Last year, the company also for the first time offered disaster recovery for hospital PACS (Picture Archiving Communication Systems).

Those systems are big business, Danois said. General Electric, Siemens and Eastman Kodak build around them, and hospitals make multimillion-dollar IT purchases to get them.

But what the disaster recovery means for hospitals is that, for the first time, they can look at disaster recovery as more than an insurance question. NDMA is a fully functioning medical imaging management system. By creating a complete copy of the PACS database on i3s system, rather than having lost data or trying to restore data from linear tape—which can take more than a year to recover all data—hospitals can have almost instantaneous access.

"That capability has never before been in the marketplace," Danois said.

Hallelujah to that, said Murray Hill Radiologys Vincente.

"GE, who we were going to buy [a new 4TB system] from, would have a [disaster recovery] service, but God forbid theres a fire or flood," Vincente said. "You live and die by having these images stored, and stored properly."

When it came to Murray Hill Radiologys attention that it could export images, on a daily basis, to a very secure database backed by IBM that had multiple disaster recovery sites, both in different locations, it came as a godsend, Vincente said.

Beyond being "as secure as you can get," Vincente said, the service meant that Murray Hill Radiology didnt have to worry about needing larger real estate—which, in New York City, is a serious matter.

"In New York City, every square foot of space is a priority," Vincente said.

In addition to disaster recovery and savings on real estate and hardware, the pressure to deal with serving up the digital images in a timely manner when a patient is in the office has been lifted from the backs of IT.

"We could tie to [our scheduling and medical records] system so it would pull the images on the schedule, so we didnt have to—when the patient was here—go retrieve them," Vincente said. "It would prefetch images, and wed have them ready, in queue, the night before."

The concept was clearly a winner. But i3 was brand-spanking new, an untested commodity. So what made Murray Hill take the chance on this newcomer?

"The people who are there [Danois and Diane Hockstein, president of MyNDMA] are really in touch with what needs to happen," Vincente said.

That means that whatever bugs needed to be worked out of the system, i3 and MyNDMA were on top of it, Vincente said. For example, a priority for Murray Hill Radiology was to take all the images on its old, full-up 4TB system and migrate them to the new service.

The biggest kinks so far have been aspects of migrating images. The service has to work well with vendor hardware to push images to the wall plug, Vincente said. As it is, GE and some of the other hardware vendors write proprietary software for their piece of equipment.

For example, Vincente said that she cant just take an optical disk from a GE MRI machine and plug it into one from Siemens. Thus, Murray Hill needed a patch from GE to decode the images so they would be readable in a common format that could be accepted by i3.

Fortunately, Vincente said that GE worked to help Murray Hill, and the clinic was able to get all the images off the old system, over the course of a few months, using magnetic tape. The images are now flowing over DSLs.

But these are all mere technology tidbits. Whats really important in this story is the diagnosis of breast cancer. For that, Vincente said, "information is always key."

"When a woman has access to her medical records and doesnt have a closet full of film jackets, because [digital images are] easily stored on a CD or on the Internet, it makes for better medicine," Vincente said. "When a radiologist sits down and has previous mammos, it is the best form of medicine. Its the future—youre allowing women to take control of their medical records. And thats always good. Information is key."

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