Close
  • Latest News
  • Cybersecurity
  • Big Data and Analytics
  • Cloud
  • Mobile
  • Networking
  • Storage
  • Applications
  • IT Management
  • Small Business
  • Development
  • Database
  • Servers
  • Android
  • Apple
  • Innovation
  • Blogs
  • PC Hardware
  • Reviews
  • Search Engines
  • Virtualization
Read Down
Sign in
Close
Welcome!Log into your account
Forgot your password?
Read Down
Password recovery
Recover your password
Close
Search
Menu
Search
  • Latest News
  • Cybersecurity
  • Big Data and Analytics
  • Cloud
  • Mobile
  • Networking
  • Storage
  • Applications
  • IT Management
  • Small Business
  • Development
  • Database
  • Servers
  • Android
  • Apple
  • Innovation
  • Blogs
  • PC Hardware
  • Reviews
  • Search Engines
  • Virtualization
More
    Home Latest News

      Study Yields Biomarkers for Detecting Cancer

      By
      Stacy Lawrence
      -
      August 17, 2004
      Share
      Facebook
      Twitter
      Linkedin

        A study released this week in the journal Cancer Research announced strides in the fight against early-stage ovarian cancer with the discovery of biomarkers and the development of tools to detect it.

        Johns Hopkins School of Medicine performed the study in collaboration with diagnostic company Ciphergens Biomarker Discovery Center. Researchers discovered three novel proteins associated with early-stage ovarian cancer.

        Read the full study results at the Cancer Research site.

        The only tumor marker now available for ovarian cancer is CA125, which is approved only for monitoring recurrence. It has a sensitivity of only 30 percent to 50 percent. The study found that the three new biomarkers in combination with CA125 greatly improved sensitivity for early-stage ovarian cancer detection to 74 percent.

        About 23,000 new cases of ovarian cancer are diagnosed in the United States annually. The disease also results in more than 14,000 deaths every year. When ovarian cancer is diagnosed in its early stages, the cure rate approaches 80 percent. Most women are diagnosed with ovarian cancer in the later stages.

        /zimages/3/28571.gifAn experimental cancer-screening technique needs work, researchers say. Click here to read more.

        The study used Ciphergens SELDI-based ProteinChip System to generate protein expression profiles from serum obtained from 503 women with ovarian cancer, with benign pelvic disease, or who were healthy.

        After obtaining the samples from four hospitals, a cross-validation and independent-validation study design was employed. Researchers used a bioinformatics program to discover the three biomarkers and to generate a multimarker pattern.

        “Because of the rigorous, multi-institutional study design and the use of independent validation, we believe these results are more likely to be reproducible and therefore translated to clinical practice,” said Dr. Robert Bast, vice president of translational medicine at M.D. Anderson Cancer Center and co-author of the paper. “Diagnosis of early-stage ovarian cancer could play a critical role in decreasing the mortality from this disease.”

        The study results are being validated in a larger trial with 1,500 subjects. In order to commercialize the discovery, Ciphergen is also developing diagnostic assays.

        /zimages/3/28571.gifCheck out eWEEK.coms Health Care Center at http://healthcare.eweek.com for the latest news, views and analysis of technologys impact on health care.

        Avatar
        Stacy Lawrence
        Stacy Lawrence is co-editor of CIOInsight.com's Health Care Center. Lawrence has covered IT and the life sciences for various publications, including Business 2.0, Red Herring, The Industry Standard and Nature Biotechnology. Before becoming a journalist, Lawrence attended New York University and continued on in the sociology doctoral program at UC Berkeley.

        MOST POPULAR ARTICLES

        Android

        Samsung Galaxy XCover Pro: Durability for Tough...

        Chris Preimesberger - December 5, 2020 0
        Have you ever dropped your phone, winced and felt the pain as it hit the sidewalk? Either the screen splintered like a windshield being...
        Read more
        Cloud

        Why Data Security Will Face Even Harsher...

        Chris Preimesberger - December 1, 2020 0
        Who would know more about details of the hacking process than an actual former career hacker? And who wants to understand all they can...
        Read more
        Cybersecurity

        How Veritas Is Shining a Light Into...

        eWEEK EDITORS - September 25, 2020 0
        Protecting data has always been one of the most important tasks in all of IT, yet as more companies become data companies at the...
        Read more
        Big Data and Analytics

        How NVIDIA A100 Station Brings Data Center...

        Zeus Kerravala - November 18, 2020 0
        There’s little debate that graphics processor unit manufacturer NVIDIA is the de facto standard when it comes to providing silicon to power machine learning...
        Read more
        Apple

        Why iPhone 12 Pro Makes Sense for...

        Wayne Rash - November 26, 2020 0
        If you’ve been watching the Apple commercials for the past three weeks, you already know what the company thinks will happen if you buy...
        Read more
        eWeek


        Contact Us | About | Sitemap

        Facebook
        Linkedin
        RSS
        Twitter
        Youtube

        Property of TechnologyAdvice.
        Terms of Service | Privacy Notice | Advertise | California - Do Not Sell My Information

        © 2021 TechnologyAdvice. All Rights Reserved

        Advertiser Disclosure: Some of the products that appear on this site are from companies from which TechnologyAdvice receives compensation. This compensation may impact how and where products appear on this site including, for example, the order in which they appear. TechnologyAdvice does not include all companies or all types of products available in the marketplace.

        ×